The Musculoskeletal Tumor Society (MSTS) and the Orthopaedic Research and Education Foundation (OREF) invite clinical researchers to apply for an OREF/MSTS Clinical Research Grant in the area of clinical orthopaedic oncology as part of a grant sharing program. The PI or co-PI must be an MSTS member in good standing.
The objective of the grant is to encourage new and established investigators by providing seed and start-up funding for promising research projects that improve clinical outcomes for patients. Clinical relevance must be clearly noted in the abstract and specific aims, and be obvious from the title and the study design. Projects should be prospective, multi-institutional if necessary to meet accrual goals, and if so open to institutions of MSTS members.
Pilot studies should identify specific sources of potential longer term funding or matching funding. A total of $100,000 is available. Maximum funding will be one grant of up to a total of $100,000 over a one-to-two-year study period, conditional upon annual review for two-year studies. Projects for lesser amounts are eligible. Budget justification is necessary. Clinical projects are eligible, with clinical relevance explicitly and clearly described. Basic science proposals will not be considered (OREF has other funding mechanisms for basic science proposals). A list of MSTS research priorities follows, however other musculoskeletal oncology related topics will be considered. The application deadline is September 12, 2013.
MSTS Clinical Research Priorities
- Randomized trial of Giant Cell Tumor of Bone treatment evaluating local and systemic adjuvants (e.g., cryosurgery, PMMA cement containing bisphosphonate, SQ bisphosphonate, IV Denusomab)
- Randomized trial of Pigmented Villonodular Synovitis treatment evaluating open versus arthroscopic synovectomy and role of radiation therapy
- Randomized trial comparing clinical outcome of site specific bone metastatic lesions treated by internal fixation alone or with intralesional excision and PMMA cementation
- Randomized trial comparing endoprosthetic reconstruction with internal fixation of proximal femur metastatic disease
- Randomized trial comparing local recurrence of desmoid tumors after excision with and without radiation therapy